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South America is a treasure trove of diverse cultures, breathtaking landscapes, and unforgettable adventures. For U.S. travelers seeking the cheapest places to fly to in South America, the good news is that exploring this vibrant continent doesn't have to break the bank. With numerous affordable flights departing from major cities like New York, Miami, Houston, and Los Angeles, your dream trip is within reach.
Airfare to South America has become increasingly competitive, thanks to a variety of airlines offering budget-friendly options. Whether you're drawn to the historical richness of ancient ruins, the rhythmic beats of lively cities, or the tranquil beauty of pristine beaches, there's a destination that fits both your interests and your wallet.
Below, we've compiled a list of the 11 cheapest South American destinations to fly to from the USA in 2025. Each city offers unique experiences that cater to both casual vacationers and seasoned travelers alike.
#1. Cartagena, Colombia
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With its sun-kissed beaches and vibrant nightlife, Cartagena is a Caribbean gem rich in history and culture. Stroll through the walled Old Town, a UNESCO World Heritage site, where horse-drawn carriages navigate narrow streets lined with brightly painted buildings and bougainvillea-covered balconies. Relax on the nearby Rosario Islands, or immerse yourself in the local cuisine at bustling plazas.
Best months to fly: January, February, and March, when flights are reduced by 20–30%.
Roundtrip Flights:
- Fort Lauderdale to Cartagena: from $169
- Orlando to Cartagena: from $192
- Boston to Cartagena: from $240
- Atlanta to Cartagena: from $243
- Miami to Cartagena: from $250
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#2. Bogotá, Colombia
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Nestled high in the Andes, Bogotá is Colombia's bustling capital that seamlessly blends modernity with tradition. Explore the cobblestone streets of the historic La Candelaria district, adorned with colorful colonial buildings and captivating street art. Don't miss the Gold Museum, home to an impressive collection of pre-Columbian gold artifacts. For panoramic views of the city, take a funicular ride up to Monserrate Mountain.
Best months to fly: January, February, and March, when airfare can be up to 20% cheaper.
Roundtrip Flights:
- Orlando to Bogotá: from $189
- Miami to Bogotá: from $233
- New York to Bogotá: from $275
- Washington D.C. to Bogotá: from $277
- Chicago to Bogotá: from $286
Looking for more options? Click here to explore flights
#3. Quito, Ecuador
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Perched high in the Andes, Quito is renowned for its well-preserved historic center, another UNESCO World Heritage site. Wander through Plaza Grande, visit the stunning Basilica del Voto Nacional, and stand on the equator at the Middle of the World Monument. Quito serves as an excellent gateway to Ecuador's diverse landscapes, from volcanic peaks to lush rainforests.
Best months to fly: February, March, May and September, with fares 20–30% lower.
Roundtrip Flights:
- New York to Quito: from $285
- Miami to Quito: from $334
- Boston to Quito: from $346
- Los Angeles to Quito: from $425
- Dallas to Quito: from $435
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#4. Guayaquil, Ecuador
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As Ecuador's largest city, Guayaquil offers a lively waterfront along the Malecón 2000, where you can enjoy parks, museums, and eateries overlooking the Guayas River. Climb the 444 steps of Las Peñas neighborhood for panoramic views, and consider a trip to the nearby Galápagos Islands for an unforgettable wildlife experience.
Best months to fly: January, February, March, and November, when airfare drops by 20–25%.
Roundtrip Flights:
- Fort Lauderdale to Guayaquil: from $245
- Miami to Guayaquil: from $294
- New York to Guayaquil: from $334
- Atlanta to Guayaquil: from $366
- Los Angeles to Guayaquil: from $385
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#5. Lima, Peru
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Lima, perched on the Pacific coast, is a city where history meets culinary excellence. Visit the Huaca Pucllana archaeological site, explore the art-filled streets of Barranco, and indulge in world-renowned Peruvian cuisine featuring dishes like ceviche and lomo saltado. Lima's mix of colonial architecture and modern flair makes it a captivating destination.
Best months to fly: February, March, and May, with discounts up to 20%.
Roundtrip Flights:
- Chicago to Lima: from $270
- New York to Lima: from $350
- Austin to Lima: from $371
- Tampa to Lima: from $391
- Miami to Lima: from $414
Looking for more options? Click here to explore flights
#6. São Paulo, Brazil
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A sprawling metropolis, São Paulo is Brazil's cultural and economic powerhouse. Art enthusiasts will appreciate the São Paulo Museum of Art, while foodies can indulge in a vibrant culinary scene that reflects the city's diverse population. Don't miss Ibirapuera Park, a green oasis amid skyscrapers, perfect for relaxation and people-watching.
Best months to fly: March, April and May, with savings up to 25%.
Roundtrip Flights:
- Orlando to São Paulo: from $373
- Denver to São Paulo: from $397
- Boston to São Paulo: from $424
- Los Angeles to São Paulo: from $455
- Fort Lauderdale to São Paulo: from $504
Looking for more options? Click here to explore flights
#7. Rio de Janeiro, Brazil
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Rio de Janeiro captivates visitors with its breathtaking landscapes and vibrant culture. Bask on the iconic Copacabana and Ipanema beaches, take a cable car to the summit of Sugarloaf Mountain, and witness the awe-inspiring Christ the Redeemer statue atop Corcovado Mountain. The city's rhythm comes alive with samba beats and colorful festivals.
Best months to fly: March, April and May, when airfare decreases by 20%.
Roundtrip Flights:
- Orlando to Rio de Janeiro: from $417
- Miami to Rio de Janeiro: from $454
- Washington D.C. to Rio de Janeiro: from $525
- New York to Rio de Janeiro: from $580
- Atlanta to Rio de Janeiro: from $589
Looking for more options? Click here to explore flights
#8. Santiago, Chile
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Surrounded by snow-capped mountains, Santiago offers a blend of modernity and tradition. Visit the historic Plaza de Armas, explore the bohemian Bellavista neighborhood, and sample Chilean wines in nearby valleys. The city's efficient metro system and pedestrian-friendly streets make it easy to navigate and discover hidden gems.
Best months to fly: March, May and October, with discounts of 15–20%.
Roundtrip Flights:
- Miami to Santiago: from $410
- Washington D.C. to Santiago: from $441
- New York to Santiago: from $503
- Chicago to Santiago: from $545
- Orlando to Santiago: from $563
Looking for more options? Click here to explore flights
#9. Cusco, Peru
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Once the capital of the Incan Empire, Cusco is a city steeped in history and culture. Wander through streets lined with stone walls built by the Incas, visit the impressive Sacsayhuamán fortress, and acclimate to the altitude before embarking on the journey to Machu Picchu. The vibrant local markets offer handmade crafts and traditional textiles.
Best months to fly: January, February, March, and May, with flights discounted by 20%.
Roundtrip Flights:
- New York to Cusco: from $458
- Chicago to Cusco: from $459
- Miami to Cusco: from $464
- Washington D.C. to Cusco: from $490
- Los Angeles to Cusco: from $547
Looking for more options? Click here to explore flights
#10. Montevideo, Uruguay
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Montevideo, Uruguay's capital, is a city where laid-back coastal living meets rich history. Stroll along the Rambla, a waterfront promenade stretching for miles, explore the charming streets of the Ciudad Vieja (Old Town), and savor traditional Uruguayan barbecue at a local parrilla. The city's welcoming atmosphere makes it a delightful destination.
Best months to fly: January, February, May and October, with airfare reduced by up to 30-40%.
Roundtrip Flights:
- Atlanta to Montevideo: from $506
- Miami to Montevideo: from $567
- Orlando to Montevideo: from $634
- New York to Montevideo: from $669
- Los Angeles to Montevideo: from $714
Looking for more options? Click here to explore flights
Conclusion
From the colorful facades of Cartagena to the ancient mysteries of Cusco, South America offers an array of destinations that cater to every traveler's desires. These cities not only provide rich cultural experiences and natural beauty but also feature some of the cheapest flights to South America from the USA. By choosing the right time to travel and booking smartly, you can embark on an unforgettable journey without overspending.
To ensure you get the best deals on airfare, consider using AirTrack, the innovative Telegram bot designed to track and compare flight prices from hundreds of airlines. With AirTrack, you receive instant notifications when fares drop, helping you secure the cheapest airfare to South America effortlessly. Planning your 2025 adventure has never been easier — let AirTrack guide you to the most affordable options and turn your travel dreams into reality.
FAQ
Which South American country is the cheapest to fly to?
Colombia often tops the list as one of the cheapest countries in South America to fly to, especially cities like Bogotá and Cartagena, due to frequent flights and competitive pricing from multiple airlines.
Which airline is best for South America?
Airlines such as LATAM, Avianca, and Copa Airlines are highly regarded for their extensive routes and reasonable fares, making them popular choices for travelers seeking cheap flights to South America.
What is the safest country in South America?
Uruguay is frequently cited as one of the safest countries in South America, offering a stable political climate and low crime rates, which makes cities like Montevideo appealing to visitors.
Which is safer, Brazil or Argentina?
Both countries have areas that are safe for tourists, but generally, Argentina is considered safer than Brazil. Cities like Buenos Aires have lower crime rates compared to some major Brazilian cities.
What month is cheaper to fly to Brazil?
The months of February and March are typically the most cost-effective times to fly to Brazil. During this period, airlines often reduce fares by up to 25%, providing opportunities for cheap flights to Latin America.
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